Real Madrid will aim to bounce back from their first defeat in seven outings last time out, as they host Granada on Sunday night.
Carlo Ancelotti's men are in a slight slump, suffering a 1-0 Copa del Rey loss to Athletic Bilbao on Thursday to follow a 2-2 league draw with Elche prior to the mini-break in the season.
Los Blancos remain at the La Liga summit, however, boasting a four-point cushion between themselves and nearest challengers Sevilla.
Here's 90min's preview of this one.
How to watch Real Madrid vs Granada on TV
When is kick off? Sunday 6 February, 20:00 (GMT)
Where is it being played? Santiago Bernabeu, Madrid
What TV channel is it on? La Liga TV, Premier Sports 2 (UK), ESPN+ (US)
Highlights? La Liga Santander YouTube channel
Who's the referee? Antonio Miguel Mateu Lahoz
Real Madrid team news
There is good news for Ancelotti's side, with Dani Carvajal set to return following a period of Covid-19-enforced isolation, while Karim Benzema should also feature following a slight hamstring problem.
Mariano, however, represents a doubt for the hosts and will likely join certain absentees Ferland Mendy - who is suffering from a muscular issue - and Vinicius Jr - who is out through suspension - on the sidelines.
Read Real Madrid's predicted lineup here
Granada team news
Moreno's squad is in very good nick coming into this weekend's clash.
The visitors' boss has the option to mix his side up following their 2-0 defeat to Osasuna last time out, although a similar lineup is expected with only Neyder Lozano and Santiago Arias out through injury.
Real Madrid vs Granada head to head record
Los Blancos have been devastatingly dominant in this fixture over the years, winning 37 of the two clubs' 51 meetings while Granada have managed just six wins. There have also been eight draws.
Recent history doesn't encourage much confidence for the visitors, either. Since beating Real 1-0 in February 2013, Granada have lost each of the 13 subsequent meetings by an aggregate score of 44-7 - including a 9-1 demolition back in April 2015.
Real Madrid vs Granada prediction
A 9-1 thumping might be a bit much to expect, but anything other than a Real Madrid victory would be a shock in this one - they just love playing Granada.
Los Blancos look on course to secure the title as thing stand, while Sunday's visitors are in a somewhat precarious position as the campaign's business end approaches.
With the superior quality on show for Ancelotti's men, the hosts have the perfect opportunity to bounce back from a two-match winless streak.
Prediction: Real Madrid 4-1 Granada