Just a few days removed from their meeting in the Premier League, Manchester United and West Ham square off in the Carabao Cup third round on Wednesday.
United won on Sunday, with a late David de Gea penalty save giving them a 2-1 victory. The Hammers will be itching to get revenge in Manchester, even if both sides are likely to rotate significantly.
Here is everything you need to know ahead of the cup tie...
How to watch Man Utd vs West Ham on TV/live stream
When is kick off? Wednesday 22 September, 19:45 (BST)
Where is the match being played? Old Trafford
What TV channel is it on? Sky Sports (UK), ESPN+ (US)
Highlights? Sky Sports (UK), Carabao Cup on Quest TV (UK)
Referee? Jonathan Moss
Man Utd team news
Ole Gunnar Solskjaer is likely to rotate for this one, although he will still be eager to win as he looks to claim his first trophy at Old Trafford this season.
He will have to do without Phil Jones, Marcus Rashford, Alex Telles, Dean Henderson and Amad Diallo but every other member of his squad is in contention. This includes Edinson Cavani, who is doubtful but could feature.
West Ham team news
David Moyes has close to a clean bill of health with Winston Reid - who would be unlikely to play anyway - his only injured player.
Michail Antonio has served his suspension and will almost certainly return to the starting XI. Aside from this, Moyes seems likely to shuffle his ranks.
Man Utd vs West Ham predicted lineups
Man Utd: Heaton; Dalot, Bailly, Lindelof, Shaw; Van de Beek, Matic; Sancho, Mata, Lingard; Martial
West Ham: Areola; Fredericks, Dawson, Diop, Masuaku; Kral, Rice; Yarmolenko, Fornals, Benrahma; Antonio
Man Utd vs West Ham head-to-head record
You do not need a good memory to recall the last meeting between the two sides with United seeing off the Hammers in dramatic circumstances on Sunday.
That result was the Red Devils' 70th all-time victory over West Ham and it extended their winning run against the east Londoners to four successive games.
Overall, the Hammers have enjoyed 45 victories over United, most recently defeating them 2-0 back in September 2019.
Man Utd vs West Ham prediction
On paper, this should be an entertaining cup tie. Both sides will be fired up after facing each other in a hotly-contested game at the weekend.
While United have plenty of strength in depth, they have tended to struggle after rotating heavily in the past - and there could be a repeat of that on Wednesday. Expect this one to go the distance, eventually being settled by a penalty shootout.
Prediction: Man Utd 1-1 West Ham (Man Utd win on penalties)