Brazilian duo Eder Militao and Rodrygo are both expected to receive Spanish passports early in 2023.
Vinicius Junior was handed his Spanish documents earlier this month, meaning he no longer needs to take up one of Real Madrid's limited non-EU spots.
La Liga sides can have five non-EU players in their squad, but only three can be named in any one matchday squad, and Real have been operating at full capacity in recent seasons with Vinicius, Militao and Rodrygo.
With the former now no longer held to the rules, ESPN report that both Militao and Rodrygo are expected to receive Spanish passports in early 2023.
Should that be the case, then Real would drop down to zero non-EU players in their matchday squads, freeing up the possibility of Los Blancos signing more global talents.
Squad restrictions played a part in Real's summer transfer window, with club officials declining to pursue a move for Brazilian striker Gabriel Jesus amid concerns that they would not be able to register him.
Jesus ended up joining Arsenal from Manchester City two months before Vinicius received his Spanish passport.