The 2022/23 WSL season will kick off on Friday 16 September, after the opening weekend was postponed following the death of Queen Elizabeth II.
All fixtures up and down the football pyramid were postponed between 9-11 October as a mark of respect for the long-serving monarch, who passed away in Balmoral on Thursday,
The 2022/23 WSL season will now open with Arsenal vs Brighton at Borehamwood on Friday evening, kick off at 19:30 (BST).
Manchester United host Reading on Saturday, before Aston Villa versus Manchester City, West Ham against Everton, Leicester versus Tottenham and Liverpool against Chelsea all take place on the Sunday.
The Women's Championship, Women's National League and Women's FA Cup can also return to action this weekend, in addition to grassroots matches.
"We would like to express our thanks and gratitude to everyone across our game for their support and understanding as we paid respect to our long- standing Patron of The Football Association, Queen Elizabeth Il," an FA statement read.
"After a period of pause and reflection for our national game, we can confirm that fixtures will resume as scheduled, including matches from the Barclays Women's Super League and Barclays Women's Championship, the Emirates FA Cup Second Round Qualifying, Vitality Women's FA Cup, the National League System [NLS], Steps 1-6, including the Vanarama National Leagues, the Women's Football Pyramid [WFP], Tiers 3-7, and all matches across grassroots football in England.
"All matches held at stadiums are subject to leagues and clubs working with the relevant authorities to stage these fixtures, as usual practice.
"We will be recommending to clubs, leagues and competitions across the country that a minute's silence is observed before matches are played, and that black armbands should be worn where possible."