West Ham entertain Burnley at the London Stadium as the Hammers look to continue their push for European football next season.
David Moyes' side took a huge step towards automatic Champions League qualification after a 3-0 victory in Lyon sealed their place in the last four of the Europa League.
The Hammers will face Eintracht Frankfurt - who downed Barcelona at the Camp Nou - for a place in the final, although Moyes was keen to stress after the game that his side still have ambitions to qualify for Europe via the domestic route.
With that in mind, here's how the Hammers could line up.
1. Goalkeeper & defenders
Lukasz Fabianski (GK) - The type of goalkeeper you can rely upon. Impressive in shot-stopping situations as well as commanding his penalty area.
Vladimir Coufal (RB) - Has found it difficult to dislodge Ben Johnson this term, but he was a constant threat at Brentford last weekend.
Craig Dawson (CB) - One of the first names on the teamsheet for the Hammers, popping up with another crucial headed goal in Lyon in midweek.
Issa Diop (CB) - Likely to replace the injured Kurt Zouma at the heart of defence from last weekend's defeat.
Aaron Cresswell (LB) - His set-piece deliveries have become a huge weapon in West Ham's arsenal.
Declan Rice (CM) - West Ham's marathon man, with the midfielder set to make his 31st Premier League appearance this season. Added another vital goal in midweek when his side required it most.
Tomas Soucek (CM) - The goals have dried up for the Czech international, having netted just four times in the league after a double-figure goal return last season.
Pablo Fornals (AM) - Last scored in the 2-1 win over Aston Villa last month, with the Spaniard looking for his seventh goal of the league campaign this weekend.
Jarrod Bowen (RW) - A menace for defenders, equally capable in one-on-one duels as he is getting on the end of chances as Lyon discovered to their detriment in midweek.
Michail Antonio (ST) - The goals have dried up for the forward since the turn of the year, having netted just once since the win at Crystal Palace on New Year's Day.
Said Benrahma (LW) - Uses his diminutive frame to good effect, gliding through pressure to create moments of danger.