Villarreal host Bayern Munich on Wednesday night in the first leg of the pair's Champions League quarter-final tie.
Unai Emery's Europa League winners shocked Juventus in the first knockout round and have gone further in the competition this season than they have done since a last-eight appearance in 2009.
Bayern, meanwhile, made light work of the last round as they thrashed Red Bull Salzburg 8-2 on aggregate thanks to running up the score-line in the second leg in Munich in early March.
This is everything you need to know about this week's meeting...
How to watch Villarreal vs Bayern Munich on TV/live stream
When is kick off? Wednesday 6 April, 20:00 (BST)
Where is the match being played? Estadio de la Ceramica
TV channel/live stream? BT Sport 3 (UK), fubo TV (US)
Highlights? BT Sport YouTube
Referee? Anthony Taylor (ENG)
VAR? Stuart Attwell (ENG)
Villarreal team news & predicted lineup
Left-back Alberto Moreno is the only certainty to miss this game through injury, with Pervis Estupinan and Alfonso Pedraza the potential stand-ins.
Gerard Moreno should start only his second game in all competitions since returning from a recent spell out with a calf injury.
Predicted lineup: Rulli; Foyth, Albiol, Torres, Estupinan; Pino, Capoue, Parejo, Lo Celso, Danjuma; Moreno
Bayern Munich team news & predicted lineup
Alphonso Davies remains sidelined but is at least back in training following a recent heart concern, while Eric Maxim Choupo-Moting is expected to miss out following a positive Covid-19 test.
Corentin Tolisso is an injury doubt after being forced off against Freiburg at the weekend.
Predicted lineup: Neuer; Pavard, Sule, Upamecano, Hernandez; Kimmich, Goretzka, Muller; Sane, Lewandowski, Coman
Villarreal vs Bayern Munich score prediction
Bayern remain among the favourites to lift the trophy at the end of the season and have the attacking ability to blow away an opponent if the mood strikes them, as they showed against Salzburg in the last round.
Villarreal have done well to get this far, but their domestic results over the past month have been surprisingly poor - they have lost against Osasuna, Cadiz and Levante without scoring since 5 March. That isn't the best preparation for this one.