US Open Cup round-of-16 draw: El Trafico, Florida derby & more

LA Galaxy vs LAFC is the standout round-of-16 fixture.
LA Galaxy vs LAFC is the standout round-of-16 fixture. / Dave Bernal/ISI Photos/GettyImages
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13 teams from Major League Soccer have learned their US Open Cup fate following the round-of-16 draw.

The likes of LAFC, Nashville SC, and NYCFC are among the favorites to lift the coveted trophy after beating the Portland Timbers, Atlanta United, and Rochester New York FC, respectively, in the previous round.

USL is also still strongly represented by three teams: Union Omaha, Louisville City, and the Sacramento Republic. The trio will do well to reach the quarter-finals, though, after being paired with MLS clubs in the next round.

All round-of-16 games will be played on May 24 and 25.

Take a look at the full draw, including El Trafico and Florida derby match-ups:

1. Northeast region

Can NYCFC add the Open Cup to their MLS Cup triumph?
Can NYCFC add the Open Cup to their MLS Cup triumph? / Gregory Fisher-USA TODAY Sports
  • New York Red Bulls vs Charlotte FC
  • New York City FC vs New England Revolution

2. Southeast region

Nashville came from 2-0 down to beat Atlanta United 3-2.
Nashville came from 2-0 down to beat Atlanta United 3-2. / Andrew Nelles / Tennessean.com / USA
  • Orlando City vs Inter Miami
  • Louisville City vs Nashville SC

3. Central region

The Dynamo won the Open Cup in 2018.
The Dynamo won the Open Cup in 2018. / Troy Taormina-USA TODAY Sports
  • Sporting Kansas City vs Houston Dynamo
  • Minnesota United vs Union Omaha

4. West region

Javier Hernández, Jesús Murillo
El Trafico is the pick of the draw. / Shaun Clark/GettyImages
  • LA Galaxy vs LAFC
  • Sacramento Republic vs San Jose Earthquakes