Tottenham make the daunting trip to Anfield to face Liverpool as Antonio Conte's side look to keep the pressure on Arsenal in the race for the top four.
Defeat could see Spurs fall five points behind their north London neighbours this weekend, with Arsenal set to host Leeds the following day.
The two square off in the rearranged north London derby next Thursday evening and Spurs will be keen to stay within touching distance of the Gunners with barely any margin for error between now and the end of the campaign.
Here's how Spurs could line up for this one.
Tottenham predicted lineup vs Liverpool (3-4-3)
Hugo Lloris (GK) - Prone to an error or two, but his general consistency for Tottenham over the years has been remarkable.
Cristian Romero (CB) - His crunching tackle in midfield sent Spurs on their way to double their advantage against Leicester last weekend.
Eric Dier (CB) - Conte's side look a considerably more resolute outfit with the Englishman at the heart of the defence.
Ben Davies (CB) - His comfort in possession allows Spurs to play out of pressure in defence.
Emerson Royal (RWB) - Endured a torrid campaign in north London, but he has recovered his composure in recent weeks.
Rodrigo Bentancur (CM) - Always available to receive a pass from the defence, constantly looking to progress Spurs into dangerous areas.
Pierre-Emile Hojbjerg (CM) - Complements Bentancur in the centre of the pitch, providing steel and energy without the ball.
Ryan Sessegnon (LWB) - Has the stamina to get up and down the line effortlessly, but he lacks a consistent end product.
Dejan Kulusevski (RW) - Came off the bench last weekend to provide a pair of assists, underlining his importance to this Spurs side.
Harry Kane (ST) - Boasts a strong record against Liverpool, netting seven times against the Reds since his first appearance in 2015.
Heung-min Son (LW) - Netted his 10th goal with his left foot in the win over Leicester, making him only the second right-footed player to score ten or more goals in a single season with his weak foot.