Under the management of Antonio Conte, Inter were in the title race for much of last season before a run of inconsistent form scuppered their attempt at winning the Scudetto. Alongside this, Inter reached last season's Europa League final only to go down 3-2 to Sevilla.
Conte will be aiming to start this season as they mean to go on. However, their opponents Fiorentina are a handy side with attackers that can hurt any team in the division. Inter should be guard against complacency.
This is the team we think they should field on Saturday:
1. Goalkeeper and Defenders
Samir Handanovic (GK) - The Slovenian goalkeeper was responsible for Inter having the best defensive record in Serie A last season. A solid base for Conte to build on.
Achraf Hakimi (RWB) - Having signed for a whopping £36.5m from Real Madrid, expectations surrounding the young Moroccan are high. Impressed on loan at Borussia Dortmund and the dynamic wing back should settle in well in Italy.
Alexsander Kolarov (CB) - Joined on a free transfer from Roma this summer and will be hoping to make his Inter debut on Saturday. Still a menace from free-kicks.
Alessandro Bastoni (CB) - Only 21 years old, Bastoni recently received his first call up to the Italian national team this month.
Milan Skriniar (CB) - The Slovakian centre back made 32 league appearances for Inter last season, demonstrating his importance to the team. Will need to manage Chiesa on Saturday.
Ashley Young (LWB) - The former Manchester United man has enjoyed something of a renaissance in Italy, a development that even extended to his hairline. Much better player than social media would believe.
Stefano Sensi (CM) - Impressed sufficiently on loan last season to join the club permanently over the summer. The 25-year-old is noted for his vision, technique and eye for goal.
Marcelo Brozovic (CM) - The Croatian international is a versatile player that can be utilised anywhere across the midfield. The kind of player that every championship-contending team needs in their lineup.
Nicolo Barella (CM) - Capped 14 times by Italy, Barella has been criticised by some for his outspokenness on the pitch. However, this cannot overshadow the immense quality the midfielder possesses.
Lautaro Martinez (ST) - The Argentine forward has been subject of reported interest from Barcelona this summer - and it's not hard to see why. Martinez scored 21 goals last season, including seven in the Europa League. Potential match winner.
Romelu Lukaku (ST) - Despite scoring an own goal in the Europa League final, Lukaku had a successful first season in Italy. Having slimmed down, the Belgian scored 34 goals in all competitions equalling Ronaldo's record from the 1997-98 season.