The Serie A fixtures for the 2021/22 season have been released with champions Inter kicking off their title defence at home to Genoa, while Massimiliano Allegri's first game back at the helm of Juventus will be away at Udinese.
The first round of matches will take place on the weekend of August 22 with the final matchday scheduled for May 22, and for the first time ever the second half of the Serie A season won't mirror the first.
Simone Inzaghi's first experience of the Derby della Madonnina will take place on November 7 with Milan classed as the home team, while the reverse fixture is scheduled for February 26.
Other notable outings for the reigning Italian champions see them face Juventus in the Derby d'Italia at home on October 24, with their trip to the Allianz Stadium pencilled in for April 3.
Massimiliano Allegri will be looking to guide Juve back to the top of Serie A after they failed to secure the Scudetto for the first time since 2011 last season.
The Old Lady travel to city rivals Torino in the Derby della Mole on October 3 with the reverse fixture on February 20, while they'll host Milan on September 19 before a trip to San Siro on January 23.
Stefano Pioli will be hoping for a similar start to this season as his Milan side experienced in the 2020/21 campaign after they sat top of Serie A following an unbeaten 15-game run. I Rossoneri will begin their campaign with a trip to Sampdoria before their first home game of the season against Hellas Verona.
Serie A has been full of managerial changes over the past few months, perhaps the most high-profile of which being the arrival of Jose Mourinho at Roma.
The former Chelsea boss' first game back in Italy comes as Roma face Fiorentina while he'll no doubt be relishing his first meeting with old side Inter on December 5.
Opening day fixture list in full
Bologna vs Salernitana
Cagliari vs Spezia
Empoli vs Lazio
Verona vs Sassuolo
Inter vs Genoa
Napoli vs Venezia
Roma vs Fiorentina
Sampdoria vs Milan
Torino vs Atalanta
Udinese vs Juventus
(Provided dates are subject to change)