Paris Saint-Germain have confirmed that forward Kylian Mbappe has joined team-mates Neymar and Mauro Icardi on the treatment table, with the star trio all set to miss Wednesday's meeting with RB Leipzig in the Champions League.
Mbappe was the last of the three to be standing, lining up for the recent 3-0 win over Nantes alongside Pablo Sarabia and Moise Kean, but after offering up a goal and an assist, he was forced off with a muscle injury midway through the second half.
The 21-year-old's fitness will be reassessed in 48 hours, meaning he may be back in time to face high-flying Rennes on Saturday, but both Neymar and Icardi are out until after the international break comes to an end.
Manager Thomas Tuchel, who will also be without Marco Verratti and Julian Draxler, is now going to have to get creative against Leipzig.
Angel Di Maria, who has been suspended for PSG's last four league games because of his involvement in a brawl against Marseille earlier in the season, will likely line up alongside Kean and Sarabia, with academy stars Alexandre Fressange and Bandiougou Fadiga waiting in the wings. Jese Rodriguez did not make the Champions League squad.
Wednesday's game isn't being seen as a must-win for PSG just yet, but after one win and one loss in their opening two games, the French champions known they cannot afford to drop many more points at this early stage of the competition.
Tuchel's side currently sit second in the group on goal difference, ahead of Leipzig but three points behind leaders Manchester United, who will expect to make it three wins out of three when they meet Turkish side Istanbul Basaksehir on Wednesday.
A loss to Leipzig would leave PSG with a lot of ground to make up, but Tuchel will have to rely on his fringe players to get the job done this time.