Niklas Sule and Leon Goretzka both look set to miss Bayern Munich's second leg against Paris Saint-Germain in the Champions League next week.
Bayern were defeated 3-2 in the first leg and travel to Parc des Princes for the second game where they will need to score at least two goals to turn the tie on its head.
Die Roten were already plagued with injuries to key names heading into the repeat of last season's final, but BILD now report that the pair both suffered muscle injuries in the game and are 'almost certain' to miss the second leg.
Goretzka was forced off just over half an hour into the game which gave Bayern a bigger headache than they wished for having conceded after three minutes. Their problems worsened, however, when Sule was also forced off three minutes before half time, also with an injury concern.
The pair join the likes of Robert Lewandowski, Douglas Costa, Serge Gnabry and Corentin Tolisso on the treatment table, which has left head coach Hansi Flick with a largely depleted first team squad. Should they miss out, the prospect of going to Paris and turning around the tie feels even more of an uphill battle for the 2019/20 Champions League winners.
The injuries also jeopardise Bayern's domestic fortunes. For all of last season's dominance where they swept up a treble and finished the campaign with a 30 match unbeaten run, this season hasn't been as dominant.
They sit seven points clear of second-placed RB Leipzig in the Bundesliga, but still have to face third place Wolfsburg and could see their lead at the top reduced once more.
Flick now faces a big test ahead of the second leg, but has welcomed back midfielder Marc Roca to training and could deploy both Jerome Boateng and Jamal Musiala to patch up the side.