Italy are gunning for their first Euros title since 1968, but they'll have to go through Belgium to keep the dream alive.
With France out of the tournament, this is a battle between arguably the two favourites to lift the trophy, and Italy will know they will have to be at their best to survive against Roberto Martinez's Red Devils.
Here's how they could line up.
1. Goalkeeper & Defenders
Gianluigi Donnarumma (GK) - The soon-to-be PSG man conceded his first goal of the summer last time out against Austria, so he'll be determined to get a clean sheet streak started again.
Giovanni Di Lorenzo (RB) - Di Lorenzo embarked on a ridiculous run against Austria and deserves to keep his spot in the squad for that highlight alone.
Leonardo Bonucci (CB) - One of the top-performing defenders of the summer, captain Bonucci will not be getting dropped anytime soon.
Giorgio Chiellini (CB) - After missing the games against Wales and Austria, the veteran Chiellini is expected to start in Munich in place of Francesco Acerbi.
Leonardo Spinazzola (LB) - Few players will come away from Euro 2020 with the kind of boost to their stock that Spinazzola has enjoyed. He's been brilliant.
Marco Verratti (CM) - Verratti put on a masterclass against Austria and already has some of Euro 2020's best creation statistics, despite barely even playing.
Jorginho (CM) - The Chelsea man has taken his game to new heights this summer and looks incredibly dangerous whenever he is on the ball.
Matteo Pessina (CM) - Pessina bagged the winner against Wales and then came off the bench to score the decisive strike against Austria. He deserves a start more than anyone.
Domenico Berardi (RW) - Now linked with a move to Leicester City, all eyes will be on Berardi, who will hope to start over the in-form Federico Chiesa.
Ciro Immobile (ST) - Up against an attacking team like Belgium, Immobile will hope to enjoy a little more space and might finally start showing the kind of prolific form we all know is in there somewhere.
Lorenzo Insigne (LW) - He might cut inside and shoot on his right foot a little too often, but Insigne is still Italy's best winger.