Fresh from Coppa Italia success, Inter travel to face Cagliari with their defence of the Scudetto on the line.
The Nerazzurri could be facing up to a five-point deficit by the time of kick off in Sardinia, with league leaders Milan set to entertain Atalanta earlier in the day.
Any slip-ups from their neighbours could present Simone Inzaghi's side with the chance to go top heading into the final game of the season, with Inter set to host Sampdoria.
Here's how the Nerazzurri could line up.
Inter predicted lineup vs Cagliari (3-5-2)
1. Inter (3-5-2)
Samir Handanovic (GK) - Has endured a turbulent campaign, but he will be keen to add another Scudetto to his trophy cabinet.
Milan Skriniar (CB) - The Slovakian has played more minutes than any other outfield player for Inter this term.
Stefan de Vrij (CB) - A cerebral defender, proving very adept at covering space and holding the defensive line.
Alessandro Bastoni (CB) - Back involved in midweek after recovering from a calf injury, with Inter having missed his defensive qualities in recent weeks.
Denzel Dumfries (RWB) - Could return to the starting XI after he dropped to the bench for the victory over Juventus.
Nicolo Barella (CM) - The Italian's ten assists for Inter in Serie A this season is bettered only by Calhanoglu.
Marcelo Brozovic (CM) - Everything flows through the Croatian for Inter, who is somehow always available to receive in space.
Hakan Calhanoglu (CM) - Boasts the most assists in the league this season after arriving from across the city.
Ivan Perisic (LWB) - Netted twice in extra time against Juventus in midweek to power Inter to Coppa Italia glory.
Lautaro Martinez (ST) - The Argentine is closing in on 20 goals for the season in Serie A.
Edin Dzeko (ST) - Has proven a good foil for Martinez this season, capable of doing the physical side of the game.