Inter will be looking to bounce back from their midweek Champions League defeat to Liverpool when they host Sassuolo in Serie A.
The Nerazzurri relinquished top spot in the league after their 1-1 draw with Napoli last weekend, making it consecutive games without a victory for the reigning champions.
Simone Inzaghi will be keen to re-establish Inter's authority in Serie A and it's in these type of fixtures where there's very little margin for error for title challenging sides.
Here's how Inter could line up...
1. Goalkeeper & defenders
Samir Handanovic (GK) - Hardly covered himself in glory attempting to save Roberto Firmino's header in midweek.
Milan Skriniar (CB) - Has received just two yellow cards this season despite his perceived aggressive streak on the pitch.
Stefan de Vrij (CB) - A cerebral defender, although he will still be kicking himself that he allowed Olivier Giroud to spin him so easily in the recent Milan Derby.
Alessandro Bastoni (CB) - Boasts a cultured left foot and has shown his threat from long-range with a couple of excellent goals this season.
2. Midfielders & wing-backs
Matteo Darmian (RWB) - Could replace Denzel Dumfries who, for his undoubted quality, has started to look leggy in recent weeks.
Nicolo Barella (CM) - No player has created more 'Big Chances' for Inter this season and they certainly missed his creativity in midweek.
Marcelo Brozovic (CM) - Attempted the most passes for Inter this season, highlighting his influence in dictacting play for Inzaghi's side.
Hakan Calhanoglu (CM) - Eight assists in the league this term ranks him as Inter's most prolific creator this term.
Ivan Perisic (LWB) - The arrival of Robin Gosens last month has thrown the Croatian's longer-term future in Milan into doubt.
Alexis Sanchez (ST) - Has found it difficult to dislodge Lautaro Martinez this season, but he has thoroughly impressed whenever he's been given the chance.
Edin Dzeko (ST) - Netted his 10th goal of the Serie A campaign in Naples last weekend.