Juventus duo Giorgio Chiellini and Aaron Ramsey will not be involved against Lazio on Sunday, and have both been left out of the travelling squad after suffering injuries.
The pair both started the Bianconeri's Champions League clash with Ferencvaros on Wednesday, a game which Andrea Pirlo's men won 4-1 thanks to goals from Alvaro Morata (2), Paulo Dybala and a Lasha Dvali own goal.
Ramsey suffered a thigh injury during the victory over Ferencvaros, and Juve confirmed the following day that he had suffered a low-grade injury following medical tests. As a result, he will be unable to feature against Lazio.
A brief statement read: "Aaron Ramsey, who was substituted off during last night’s match, was subjected to examinations at J | Medical this morning, which revealed a low-grade injury to the rectus femoris muscle of the right thigh. In 10 days it will be re-evaluated again."
Ramsey had initially been selected in the Wales squad for their upcoming clashes, but the Football Association of Wales later confirmed on their official website that the midfielder has been forced to withdraw through injury.
As for Chiellini, he will miss out on the trip to face Lazio after suffering another muscle problem in his left thigh during training on Saturday. It is unclear how serious his injury is at this current moment, but the Italian giants state that he will be looked at again in the coming days.
Pirlo's men come into Sunday's game in third place in Serie A, four points behind leaders Milan and just two points ahead of Lazio - who are currently ninth.