The Africa Cup of Nations always proves to be one of the most exciting continental tournaments, drawing in audiences of millions from across the globe.
But the 2021 edition was pushed back to January 2022, meaning it will once again cause disruption for most Premier League sides.
The good news is the release date for those partaking in the tournament has been moved to January 3, meaning top flight clubs will get one or two more games out of their African stars. The tournament will conclude on February 6.
Here's the full list of Premier League players jetting off to Cameroon for the finals.
Thomas Partey (Ghana)
Mohamed Elneny (Egypt)
Pierre Emerick Aubameyang (Gabon)
Nicolas Pepe (Ivory Coast)
Star striker Aubameyang is among Arsenal's players jetting off to AFCON, though he has been omitted from recent matchday squads and stripped of the captaincy due to a disciplinary breach anyway.
2. Aston Villa
Bertrand Traore (Burkina Faso)
The Villa duo have been on the fringes of the squad this season and their absences shouldn't have too much of an impact on proceedings in the West Midlands.
Frank Onyeka (Nigeria)
Summer signing Onyeka is the only player from Brentford off to the tournament.
4. Brighton & Hove Albion
Yves Bissouma (Mali)
Ulrick Eneme Ella (Gabon)
After a three-year absence, box-to-box midfielder Bissouma has been recalled by his country as they look to conquer Africa.
Maxwel Cornet (Ivory Coast)
After such a fine start to life in England, Burnley will miss Cornet in their fight for Premier League survival.
Edouard Mendy (Senegal)
While the Blues will be without their imperious goalkeeper in January, they've been handed a boost after Hakim Ziyech was left out of Morocco's squad.
7. Crystal Palace
Jordan Ayew (Ghana)
Cheikhou Kouyate (Senegal)
Wilfried Zaha (Ivory Coast)
Crystal Palace's already thin squad will be pushed to the limit in the absence of three key men.
Alex Iwobi (Nigeria)
While Iwobi has been called up to AFCON, the perennially-injured Jean-Philippe Gbamin has not.
9. Leeds United
Good news, Leeds fans - none of your players will be missing through international duty in January.
Now, if only the recent rise in injuries will subside...
10. Leicester City
Daniel Amartey (Ghana)
Kelechi Iheanacho (Nigeria)
Nampalys Mendy (Senegal)
Wilfred Ndidi (Nigeria)
Brendan Rodgers' squad is being decimated by injuries. He won't be pleased to see four of his stars jet off this January.
Naby Keita (Guinea)
Sadio Mane (Senegal)
Mohamed Salah (Egypt)
Eesh. Liverpool will almost certainly be hit hardest by AFCON absences.
12. Manchester City
Riyad Mahrez (Algeria)
Algeria captain Mahrez is off to AFCON - however will Man City cope without one of their several star wide forwards?
13. Manchester United
Eric Bailly (CB)
Man Utd should be well-stocked at centre-back in Bailly's absence providing Raphael Varane and Victor Lindelof's returns are smooth.
Like Leeds, Newcastle's fight for survival will be helped by the fact they have no representatives at AFCON.
15. Norwich City
See: Leeds, Newcastle.
Moussa Djenepo (Mali)
While tricky winger Djenepo will not be available for Ralph Hasenhuttl's selection for the next month or so, Mohammed Salisu has not been called up by Ghana and will remain in England.
17. Tottenham Hotspur
Spurs are the only top four-contender without a player heading to AFCON.
Emmanuel Dennis (Nigeria)
Adam Masina (Morocco)
Imran Louza (Morocco)
Ismaila Sarr (Senegal)
William Troost-Ekong (Nigeria)
Godspeed to Claudio Ranieri and the remainder of his Watford contingent who face six-pointers against Newcastle and Norwich in January.
19. West Ham United
Said Benrahma (Algeria)
Benrahma's breakout season at London Stadium will be put on hold while he's at AFCON.
20. Wolverhampton Wanderers
Willy Boly (Ivory Coast)
Romain Saiss (Morocco)
Wolves have one of the smallest squads in the Premier League as it is and will have to get by without these two centre-backs.