Borussia Dortmund's title challenge may be over by the time they play Mainz on Wednesday, with Bayern Munich having the opportunity to seal the title against Werder Bremen on Tuesday. However, the Black and Yellows will still be hungry for three points as they look to secure second place and extend the gap between themselves and third-placed RB Leipzig.
A defeat to Augsburg at the weekend has left Mainz dangerously close to the relegation zone, just three points ahead of Düsseldorf, and Die Nullfünfer will have to be at their utmost best if they're to take anything from Dortmund.
Where to Watch
Dortmund will once again be without Marco Reus and Thomas Delaney, with a return date currently unclear for both. Mahmoud Dahoud and Dan-Axel Zagadou are both close to a return but won't be ready for Wednesday's game – but after missing a couple of games through injury, star man Erling Haaland returned off the bench at the weekend and is expected to feature once again.
Mainz continue to be without first-choice goalkeeper Robin Zentner, with the 25-year old still out with a ruptured cruciate ligament, and striker Taiwo Awoniyi is also set to miss Wednesday's game after suffering a concussion at the weekend.
Borussia Dortmund: Burki, Piszczek, Hummels, Akanji, Hakimi, Can, Witsel, Guerreiro, Brandt, Sancho; Haaland.
1. FSV Mainz 05: Müller, Brosinski, St. Juste, Niakhaté, Mwene, Barreiro, Latza, Oztunali, Quaison, Onisiwo; Mateta.
Head to Head Record
Dortmund have reigned supreme over Mainz in recent years, with Achim Beierlorzer's men only winning one of the last ten league meetings between the sides.
The Black and Yellows won the reverse fixture earlier in the season 4-0 and will be looking to do the double over Mainz for the second straight season.
Borussia Dortmund have been in great form following the Bundesliga's return and have won all but one game, a loss against league leaders Bayern Munich. In six games back, Lucien Favre's men have looked fantastic defensively, conceding only two goals.
Mainz have struggled to muster up any sort of consistent form following the league's return, losing three, drawing two and winning one of their last six games. Their only win since the restart was a 2-0 triumph away at Frankfurt.
Here's how the sides have looked over their last five games.
Fortuna Düsseldorf 0-1 Borussia Dortmund (13/6)
Borussia Dortmund 1-0 Hertha BSC (6/6)
SC Paderborn 07 1-6 Borussia Dortmund (31/5)
Borussia Dortmund 0-1 Bayern Munich (26/5)
Wolfsburg 0-2 Borussia Dortmund (23/5)
1. FSV Mainz 05
1. FSV Mainz 05 0-1 Augsburg (14/6)
Eintracht Frankfurt 0-2 1. FSV Mainz 05 (6/6)
1. FSV Mainz 05 0-1 Hoffenheim (30/5)
1. FC Union Berlin 1-1 1. FSV Mainz 05 (27/5)
1. FSV Mainz 05 0-5 RB Leipzig (24/5)
While both sides will be desperate to land the three points, Dortmund's talent will shine through and secure all three points. Haaland's return coupled with Dortmund's excellent defence will be too much for Mainz, and Favre's men should be on their way to a fairly straightforward win.
Prediction: Borussia Dortmund 3-0 1. FSV Mainz 05