Barcelona have confirmed that Philippe Coutinho faces three months on the sidelines having undergone successful knee surgery.
The Brazilian has endured a torrid time since his move from Liverpool to Camp Nou in January 2018 and has struggled to maintain a regular place in the starting XI.
Last season he was shipped out on loan to Bundesliga champions Bayern Munich, where he again struggled to cement his place in the first team before an injury saw him miss eight of the club's final nine league games.
However, Coutinho suffered a tear to his meniscus having come off the bench in Barça's 1-1 draw with Eibar on Tuesday, and the club have confirmed via their official website that he's been forced to undergo surgery on his left knee and could now miss as much as three months of the season.
While the news will undoubtedly come as a blow to Koeman, the emergence of Pedri in the first-team setup means Barça are well equipped to deal with the Brazilian's absence.
Since arriving from Las Palmas in July in a deal believed to be worth €5m (£4.4m), the Spain Under-21 international has settled seamlessly into life in Catalonia, appearing in every one of Barcelona's La Liga matches this season.
The Blaugrana have struggled to keep pace with leaders Atletico Madrid this season and already find themselves ten points adrift of Diego Simeone's men.
The midweek draw with Eibar was just the latest in a string of disappointing results for Barcelona who currently sit sixth in the table. Koeman's side travel to SD Huesca on Sunday as they look to close the gap on those ahead of them.