Isco is the most notable absentee from the latest Spain squad, as manager Luis Enrique announced a 23-man contingent to face Norway and Malta in this month's Euro 2020 qualifiers.
The 26-year-old Real Madrid playmaker has not played a full 90 minutes in 2019 and was largely f
However, there is room for several new picks from Enrique, including Jesus Navas, whose last international cap came in 2014 and Athletic Bilbao forward Iker Muniain, whose sole appearance for Spain was back in 2012.
In-form Getafe striker Jaime Mata, Sevilla defender Sergi Gomez, Real Betis midfielder Sergio Canales and Napoli's Fabian Ruiz all have the opportunity to earn their first caps for their country.
Enrique has selected just four players who currently ply their trade outside of Spain's La Liga: David de Gea (Manchester United), Kepa (Chelsea), Juan Bernat (PSG) and Fabian (Napoli). Dani Carvajal's absence through injury means there are only three Real Madrid players in the squad, while Barcelona also have three representatives.
Spain take on Norway at the Mestalla on Saturday 23 March, before travelling to Malta on Tuesday 26 March.
Goalkeepers: Kepa Arrizabalaga, David de Gea, Pau Lopez
Defenders: Jose Gaya, Jordi Alba, Juan Bernat, Mario Hermoso, Iñigo Martinez, Sergio Ramos, Sergi Gomez, Sergi Roberto
Midfielders: Jesus Navas, Sergio Busquets, Rodri, Dani Ceballos, Fabian Ruiz, Dani Parejo, Sergio Canales
Forwards: Marco Asensio, Rodrigo, Alvaro Morata, Iker Muniain, Jaime Mata