Southampton travel to London to face Chelsea in their first fixture of the new year. Manager Ralph Hasenhuttl has managed to give the Saints some hope since taking charge, but after back-to-back losses in their last two matches they need to gain some breathing room in the standings.
The Saints will miss Pierre-Emile Højbjerg who has earned another suspension, this time against Manchester City, meaning the rest of the midfield will have to step up their game once more.
Here is how Southampton could line up on Wednesday:
1. Goalkeepers & Defenders
Alex McCarthy (GK) - Despite conceding three goals against Manchester City, McCarthy could not be blamed for the defeat and will keep his place between the sticks.
Yan Valery (RWB) - Valery came off the bench in the Saints' last effort and could be set to start against Chelsea.
Jack Stephens (CB) - He will not be pleased with his performance against City, and will look to repair his image against the Blues' attacking trio.
Maya Yoshida (CB) - The Japanese international should remain in the squad as part of a back three.
Jan Bednarek (CB) - Polish international Bednarek will hope to have a better performance this time around.
Matt Targett (LWB) - The 23-year-old has only played nine games in the Premier League season but has provided two assists, and he will be looking to add to his tally against a top-tier side.
James Ward-Prowse (RM) - Despite scoring on the wrong end against City, Hasenhuttl praised his performance after the match and will probably let him keep his place in the starting XI.
Mario Lemina (CM) - Lemina has played 18 Premier League matches this season and will keep his place as Hasenhuttl tries to build a consistent starting side.
Stuart Armstrong (CM) - With Højbjerg suspended, Armstrong is likely to take his place in midfield and will hope to make a good impression against Chelsea.
Oriol Romeu (CM) - The Spanish midfielder will have to be at his best if he is to match the pace of N'Golo Kante and Jorginho.
Mohamed Elyounoussi (LM) - Elyounoussi has yet to score for Southampton, and will hope to start the new year on the scoresheet.
Danny Ings (ST) - The Liverpool loanee is the Saints' top scorer this season with seven goals from 14 appearances. After being rested earlier in the week, Ings is expected to return to the starting lineup and make the same impact he did against Arsenal.