17th placed Southampton make the 644-mile round trip to face 16th placed Newcastle United on Saturday afternoon, for a what could be a hugely significant match in the battle to stay in the Premier League.
The Saints won just one of their last 15 Premier League games, while the only defeats Newcastle have suffered since the turn of the year have come away at Manchester City and Liverpool.
Here is all you need to know about a potentially crucial match.
Goals are often a feature of clashes between these two, with the sides drawing 2-2 at St Mary's earlier in the season.
They also produced a thrilling match in February 2013. Southampton, who were managed by
Dwight Gayle vs Shane Long
Both Newcastle and Southampton have struggled for goals this season. Southampton have scored 29 goals in 29 matches with Newcastle finding the net 27 times.
Only Huddersfield Town and West Brom have scored less. The Saints' top scorer, Charlie Austin, is currently out injured so responsibility for goals falls onto the shoulders of Shane Long, who has only one goal this season. Newcastle's top scorer is Dwight Gayle, who only has five.
Considering how important a victory could be for either side this weekend, an attacking game seems unlikely. Newcastle will be hoping to build on that victory over Manchester United and the home crowd at St James' Park could well help them over the line.
Prediction: Newcastle 2-0 Southampton