Bournemouth's four match unbeaten run in the Premier League began with a controversial 3-3 draw against West Ham on Boxing Day. The Cherries now travel to east London looking to build on their impressive 2-1 win over Arsenal last weekend.
Despite their upturn in form, Eddie Howe's men were dumped out of the FA Cup in midweek, losing to League One Wigan Athletic. However, the side that takes the field at the London Stadium on Saturday will be much changed.
Asmir Begović will likely continue in goal as Howe's undisputed number one choice.
Bournemouth's defence has remained largely unchanged throughout the course of the season.
Club-record signing Nathan Aké has formed a good partnership with Steve Cook while Steve Francis and Adam Smith provide with the width. Both Tyrone Mings and Brad Smith have been long term injuries for Eddie Howe's side.
Jordan Ibe fired home the winner against Arsenal on Sunday and he will be once again an integral part to this Bournemouth side. Lys Mousset came on and made a real impact against the Gunners and could be rewarded with a rare start in midfield.
Lewis Cook and Dan Gosling should both retain their places.
Jermain Defoe will miss a match against one of his former clubs because of an injury that is likely to keep him out until March. Ryan Fraser is likely to partner Callum Wilson up front.
Wilson could be in for a frosty reception from the home fans following his controversial equaliser in the match at the Vitality Stadium on Boxing Day.