Bournemouth will look to pounce on a demoralised United side as they travel to Old Trafford during the week.
Eddie Howe's men will go into the game looking for at least a draw to ensure that they steer clear of the relegation zone but will also know how difficult it will be going up against Jose Mourinho's side.
Begovic will be the most likely choice in goal for Bournemouth, having been the main man between the sticks all season.
The Bosnian has kept four clean sheets this season but it will take a valiant effort to keep the likes of Martial, Lukaku and Rashford quiet.
The defensive line for the United encounter will likely be the same that faced Crystal Palace last weekend.
Former Chelsea man Nathan Ake is seemingly looking like he was worth every penny of the club's record fee and will look to prove himself again against a formidable United side.
The highlight of Steve Cook's season arguably was his late winner against Newcastle in early November. However, it will be his defensive work he will need to focus on against United, who boast a huge array of attacking talent.
Bournemouth's midfield will have a huge task in matching up with the likes of Nemanja Matic and Juan Mata, however, Eddie Howe's men are no strangers to a heated clash.
Howe may look to deploy Ryan Fraser and Junior Stanislas on the wings with Cook and Surman occupying the defensive midfield. Joshua King will likely be positioned just behind the striker to cause problems for the United defence.
Jermaine Defoe will look to build on an impressive showing against Crystal Palace, grabbing a brace which included a goal of the season contender.
The 35-year-old doubled his goal tally for the season against Crystal Palace and will look to put in a similar performance against a United side that will be keen to bounce back from a disappointing loss.