Away from that top-of-the-table clash, West Ham secured a vital win against Swansea, Tottenham and Manchester United handed out emphatic thrashings and Everton lost, again.
As ever, it was certainly not without talking points, and there were plenty of typically memorable moments. Here are six of them.
Best Late Winner
West Ham's Diafra Sakho scored a last-minute winner for West Ham, and Richarlison levelled in injury time for Watford at West Brom, but it was at the bet365 Stadium where the most memorable late goal of the weekend came.
Peter Crouch, 36-years-old and very much a Premier League veteran, was on hand to turn home from close range for Stoke as they secured a narrow victory over Southampton.
As Gary Lineker said on Match of the Day, "there's life in the old giraffe yet". Saturday's goal was his third in seven appearances and boss Mark Hughes has claimed he still has a "huge role" to play at the club.
Crystal Palace are very good at losing. They did it again this weekend, predictably, at Manchester United, where they willing succumbed to an inevitable 4-0 defeat.
The defending was passive, the attacking was almost non-existent and the overall performance was dismal. Roy Hodgson's shrinking demeanour on the sidelines really encapsulated his side's afternoon.
But it was nothing unexpected.
As previously mentioned, this honour goes to Manchester City, who continued their superb start to the season with an impressive, imperious win against champions Chelsea.
Kevin De Bruyne's brilliantly taken goal was enough to seal the three points, but it could have been more. This City side are beginning to look complete, a cohesive, confident unit becoming increasingly adept at carrying out Pep Guardiola's tactics and strategies.
Having swatted aside most of their opposition prior to the trip to Stamford Bridge, this was a significant statement of intent.
It's hard to look further than Philippe Coutinho's sensational long-range strike for Liverpool against Newcastle.
The Brazilian midfielder struck a 25-yard curler past a helpless Rob Elliot to equalise for his side in the draw at St James' Park.
Coutinho has now scored three goals in three games, and has made an instant impact on his return to Liverpool's first team.
Burnley, hopeless on their travels last season, have this season already secured more away points than they did in the entirety of last campaign.
Victory at Everton was their second away win and their eighth away point, and it took Sean Dyche's side impressively into sixth place.
There was another stat that proved Burnley have taken things up another level, too. The buildup for their goal included 24 passes, bettered only by Manchester City this season.
There's some competition here; Harry Kane's routine double, or Marouane Fellaini's poacher-esque brace.
Ultimately though, Kane's two strikes were the more impressive, and there are few strikers playing as well as the Spurs man in current form.
With his two goals against Huddersfield, the second an unerringly accurate left-footed shot into the far corner, Kane took his tally to 13 goals in September alone. Prolific.