Chelsea will be looking to bounce back from their disappointing 2-1 loss at home to Crystal Palace on Saturday to secure their status as champions elect, but Manchester City will provide a tough test for Antonio Conte's men.
The Citizens themselves need nothing less than a win, with Manchester United sitting five points behind City with a game in hand.
Courtois is expected to retain his place in goal, with the Belgian hoping to improve on his showing in Chelsea's defeat against the Eagles.
The Chelsea back three is likely to remain the same, with the Blues conceding just 23 times in 29 Premier League matches this season. Having struggled against the power of Benteke at the weekend, they will have another difficult task on Wednesday evening - stop City star Sergio Aguero from scoring.
Victor Moses is still struggling after missing the defeat to Palace, so Pedro is likely to fill in at wing-back.
Matic is expected to retain his place despite a poor showing at the weekend, as the midfield battle will be the key to success at Stamford Bridge. With the spotlight firmly on the Frenchman, Kante will be eager to prove that he can perform against the league's big boys.
- D. Costa19
Costa will be desperate to get on the scoresheet on Wednesday, having failed to find the target in his last 3 appearances.
With Manchester City being such a formidable attacking force, the emphasis will be placed on the Spaniard to ensure he can expose City's defensive frailties. Hazard and Willian have both impressed this season, with the Belgian winger showing the form that has made him Chelsea's talisman over the last few years.