FiveThirtyEight have predicted that City now have an 85 percent chance of winning the league title and have been projected to finish the season on 92 points.
Liverpool are predicted to beat Chelsea to finish second, but Jurgen Klopp's side only have a 13 percent chance of winning the league title.
Both City and Liverpool have a 99 percent chance of qualifying for the Champions League, while defending champions Chelsea have a 92 percent chance of making it.
Arsenal are currently placed fourth in the league table, and the supercomputer has backed Mikel Arteta's side to hold on to the coveted fourth spot. However, it has been added that the Gunners only have a 36 percent chance of securing Champions League football next season.
Top 10 in the Premier League according to the supercomputer:
1. Manchester City - 92 points
2. Liverpool - 82 points
3. Chelsea - 77 points
4. Arsenal - 65 points
5. Tottenham - 64 points
6. Manchester United - 62 points
7. West Ham - 60 points
8. Brighton - 53 points
9. Leicester - 53 points
10. Wolves - 49 points