Solskjaer made a number of changes to his starting XI for the clash at the King Power Stadium, and dropping star player Fernandes to the bench definitely seemed a gamble that did not pay off in the end. The Red Devils went on to be dumped out of the competition, as a brace from Kelechi Iheanacho and another goal from Youri Tielemans saw Brendan Rodger's progress to the semi-final.
United's only hope of winning silverware this season rests on the Europa League, and Solskjaer defended his decision to rest the Portuguese for the game. He stated per Daily Mirror: "Every team selection has reasons behind it and Bruno has played a lot of football, on Thursday night he broke all his records physically, statistically and the boy is not inhuman.
"He has played a game every three or four days and it was a chance to start both Donny [van de Beek and Paul [Pogba], but the accumulation of games maybe caught up with us. Bruno wants to play and sometimes you make decisions for the benefit of the team."
Fernandes played the full 90 minutes at San Siro on Thursday as United ran out 1-0 winners against Milan to progress to the next round of the Europa League. When asked if he'd make the same team selection again given the chance, Solskjaer replied: "I would've done the same again, the changes were necessary to do.
"We knew Paul [Pogba] wouldn't last more than an hour and I don't think I would do anything differently. What goes on behind the scenes isn't always known. I would have started the same team again. We felt they had more than 45 minutes in them, they're important players for us, that's why we started [with them]."