The two sides meet for the first time since the 2018 final, where Mohamed Salah suffered a nasty shoulder injury following a controversial tackle by Sergio Ramos. The Los Blancos captain will be missing in action this time around, but the quarter-final first leg will stir memories of a painful defeat in Kyiv for Klopp.
However, the Reds boss has insisted that while he revisited the 3-1 loss ahead of Tuesday's clash, he no longer feels an anger towards Zinedine Zidane's side. Speaking at a press conference, Klopp said: "My motivation is on the highest level because it’s the Champions League, we play Real Madrid and we want to go to the next round. It has nothing to do with 2018. When we got the draw, of course I remembered the game because it was the first time we have played each other since.
“I said after that  game that if somebody asked me in a press conference a week later or a month later if I would invite Sergio Ramos to my 60th birthday, then I would say no! Meanwhile, I would think about it again. It's not that he's not a great footballer but I didn’t like what happened that night. It was a strange night for us, but it’s long ago and I cannot get that feeling, that anger, back.
“I can only try to prepare my team to show tomorrow how good we are as a football team. It’s a strange season and a difficult season for us, but we want to show how good we are, and if we are better than Real Madrid and can score more goals, then we go to the next round. And if not then Real Madrid will.”
Liverpool come into the game on the back of three consecutive victories, and Klopp is confident his side have what it takes win on Wednesday. He added: "Our team is built for these kind of games, when we face a football-playing side. That’s why we have a chance, absolutely.
“I heard outside that everybody says Real Madrid is favourite. Great! No problem at all with that. They are used to the role, and we have no problem with the role of challenger."