Tonight they face a challenge from Kerala Blasters, who are looking to bounce back from their defeat to ATK in the season opener.
Here are four things to look forward to from this clash....
1. Kerala Blasters need to come up with a plan around Gary Hooper
The south Indian giants lost their talisman Bartholomew Ogbeche and brought in the experienced Gary Hooper.
Now, they need to plan on how to accommodate their gameplay in order to benefit Hooper to score more goals.
Hooper himself also needs to buckle up and get adjusted to a new league pretty quickly and by the time that happens, Kibu Vicuna has to devise a strategy around him.
2. NorthEast will bank on their defensive prowess
The Highlanders were incredible defensively against Mumbai City FC with epic performances coming in from Benjamin Lambot and Dylan Fox.
Apart from these two, Khassa Camara was the heartbeat of his team in their win against the Islanders.
Kerala Blasters need to know that they will have to create and take almost each of their chances if they are to cause an upset.
3. Youngsters might define the clash
Both Kerala Blasters and Northeast United have brought in some pretty good young players. Nongdamba Naorem and Ritwik Das will look to impress for Kerala Blasters.
Meanwhile, Ninthoinganba Meetei and Lalengmawia will be the crucial young talent for the Highlanders.
4. Squads and TV/Live Streaming details
Kerala Blasters FC
Goalkeepers: Albino Gomes, Bilal Husain Khan, Prabhsukhan Singh Gill, Muheet Khan.
Defenders: Costa Nhamoinesu, Nishu Kumar, Bakary Kone, Jessel Carneiro, Sandeep Singh, Abdul Hakku, Lalruatthara
Midfielders: Sergio Cidoncha, Sahal Abdul Samad, Vicente Gomez, Seityasen Singh, Rahul KP, Givson Singh, Lalthathanga Khawlhring, Yondrembem Denechandra, Nongdamba Naorem, Arjun Jayaraj, Ayush Adhikari, Jeakson Singh, Prasanth Karuthadathkuni, Ritwik Das, Rohit Kumar
Forwards: Gary Hooper, Jordan Murray, Facundo Pereyra, Naorem Mahesh Singh, Shaiborlang Kharpan.
NorthEast United FC
Goalkeepers: Gurmeet, Nikhil Deka, Sanjiban Ghosh, Subhasish Roy
Defenders: Ashutosh Mehta, Benjamin Lambot, Dylan Fox, Gurjinder Kumar, Mashoor Shereef, Nabin Rabha, Nim Dorjee, Provat Lakra, Rakesh Pradhan, Wayne Vaz
Midfielders: Federico Gallego, Imran Khan, Khassa Camara, Lalengmawia, Lalrempuia Fanai, Pragyan Gogoi, Rochharzela
Forwards: Britto PM, Idrissa Sylla, Ninthoinganba Meetei, Kwesi Appiah, Lalkhawpuimawia, Luis Machado, Suhair Vadakkepeedika
The match will be shown live on the Star Sports Network at 7:30pm and it will also be live streamed on Disney+ Hotstar and Jio TV.