Both Jurgen Klopp and Ole Gunnar Solskjaer said earlier this week that they would prevent players from travelling for games if they had to mandatorily quarantine for 10 days following their return to the UK.
The Blues currently have one player - Thiago Silva - who could be required to travel to a country on the UK Government's 'red list'. Chelsea play West Brom on April 3 - just days after players are due to return from their national teams - and Tuchel said: "I am absolutely worried because my target is to play Premier League and if I have players in quarantine, I cannot build the group that we want.
"But I am also sure that the club knows how to handle it and if it maybe is the consequence that players cannot go, then this is the consequence. The situation is extraordinary. We have to adapt and we will do this as a club. We will take the decisions. We are very concerned about the situation."
According to UK coronavirus regulations, if players travel for international duty, they would be forced to quarantine for 10 days. Liverpool would lose a number of key players, including Alisson, Fabinho, Roberto Firmino, Diogo Jota, Sadio Mane, and Naby Keita, who are all a part of their national team squads.
Similarly, for Manchester United, Bruno Fernandes is set to link up with Portugal, but could be stopped from going. If he travels, Fernandes could miss two key matches for the Red Devils - Brighton on April 3 and Tottenham on April 10 - an outcome Solskjaer is keen to avoid.