Mauricio Pochettino's Tottenham play host to bitter rivals Chelsea on Sunday afternoon, as Spurs play their first Premier League game at Wembley.
Coming into the game off the back of a clinical display against a depleted Newcastle team, Spurs meet a similarly injury and suspension hit Chelsea, making this (potentially) the perfect time for Spurs to square off with Antonio Conte's side.
With the potential to lay down the gauntlet for the rest of the season, and further add to their rivals woes, here's how Spurs might line up for this one:
The France international is surely the first name on the team sheet. Captain of both club and country, Lloris is without question one of the best stoppers in world football today.
Despite an impressive man of the match display against Newcastle, youngster Kyle Walker-Peters may not be deemed ready at this stage of his career to be thrown in against the defending Champions.
As such, expect Eric Dier to fill in at right back, having started in central midfield against Newcastle.
In midfield, Victor Wanyama is expected to return to the lineup after returning to fitness following a pre-season injury. Alongside Mousa Dembele they will expect to dominate Chelsea's makeshift midfield.
In front of them, Son Heung-min could be ready to start games after recovering from a broken arm suffered on duty with South Korea. If this is the case, Moussa Sissoko will drop out of the starting eleven.
Up front, the talismanic Harry Kane will hope to bring an end to his August hoodoo, having somehow failed to score in the the first month of the season in his teams last eleven games.
Fantasy football managers everywhere will be hoping that he can break this duck against what will be an inexperienced Chelsea back line.