Tottenham travel to Anfield on Tuesday night in the EFL Cup with a place in the quarter-finals up for grabs.
Spurs boss Mauricio Pochettino is tipped to rotate his side, giving some of his fringe players and youngsters a chance to shine.
Striker Harry Kane is nearing a return to the first-team but the game at Anfield is set to come too soon for the Englishman.
Pochettino is likely to rest Dele Alli, Christian Eriksen, and Erik Lamela as well as other regular starters in the Tottenham squad, following a run of matches in the Premier Leauge and Champions League.
Michel Vorm started Tottenham's third round victory over Gillingham in the EFL Cup and the Dutch stopper is likely to come in for Hugo Lloris.
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Kieran Trippier, Kevin Wimmer, and Ben Davies are set to come in at the back for Spurs. The trio have not seen as much first-team action as they would like, but the trip to Anfield offers a prime opportunity to impress Pochettino.
Eric Dier is set to continue at centre-back following the injury picked up by Toby Aldweireld last week against West Brom.
Vincent Wanyama and Tom Carroll look likely to start as Tottenham's midfield two, although Harry Winks will be competing for a place tomorrow evening in central midfield.
Mousa Dembele is expected to play in an advanced role behind striker Vincent Janssen, with Josh Onomah and Georges-Kévin Nkoudou offering pace out wide.
Janssen is set to start as the lone striker as the Dutchman looks to ignite his Tottenham career which has been underwhelming so far.
The 22-year-old' only goal this season came in the EFL Cup and with Kane nearing full fitness, Janssen is running out of time to cement a regular starting spot.
He will need the likes of Onomah and Nkoudou to produce the goods in attacking areas of the pitch for him to feed off.