Arsenal host Chelsea on Wednesday in the first of three clashes in January between the London rivals; as the teams were also drawn against one another in the Carabao Cup semi-finals.
With a hectic schedule over the festive period, Arsene Wenger's men have incurred a number of injuries and face various selection problems heading into the crucial game.
Here's the team the Frenchman could pick to face the reigning champions:
Chelsea legend Petr Cech keeps his place in goal against his former club.
With Nacho Monreal still out through injury, Calum Chambers should continue on the right of the Arsenal back three.
Laurent Koscielny was forced off in the second half against West Brom - with Per Mertesacker replacing him - and is a doubt for the match. Should he fail to prove his fitness before the game, the German could deputise alongside compatriot Shkodran Mustafi.
Aaron Ramsey remains out with a hamstring injury, so Jack Wilshere is set to start his sixth Premier League game in a row, the first time he's managed that feat since January 2013.
Granit Xhaka will line up alongside him, with Hector Bellerin in his usual role on the right side. Sead Kolasinac went off with a knock at the Hawthorns and will be out for around two weeks. Youngster Ainsley Maitland-Niles could fill in for the biggest test of his career so far.
Mesut Ozil missed the trip to West Brom on New Year's Eve and is unlikely to feature, with Arsene Wenger stating he has 'little chance' of playing a part on Wednesday, according to the Daily Mail.
Danny Welbeck could play in the German's absence, having been preferred in the goalless draw at Stamford Bridge in September for his defensive capabilities.
Elsewhere, Alexandre Lacazette and Alexis Sanchez pick themselves, with the latter quashing rumours of a lack of effort with a match-winning brace in the recent 3-2 win over Crystal Palace.