Real Madrid are looking to make it four wins in a row in all competitions as they welcome Espanyol to the Bernabéu.
Zidane's men impressed in their midweek Champions League clash against Napoli and another victory would see them tighten their grip on the La Liga title.
Keylor Navas will retain his place in goal.
- S. Ramos4
Real Madrid will be delighted to have both fullbacks back fully fit.
Marcelo and Carvajal have missed the past weeks down to injury but their performances against Napoli in midweek just underlined their importance to the team.
Frenchman Varane and captain Ramos should continue their fantastic partnership in the heart of the defence, despite the Spaniard picking up a slight knock in midweek.
Luka Modric made his return to the side last weekend in the 3-1 win over Osasuna and looked like he had never been away.
The Croatian has been a big miss for the league leaders but he looks to have put his injury problems behind him with decent performances this past week.
Both Kroos and Casemiro scored crucial goals in the Champions League game in midweek, with the Casemiro strike up there with one of the best goals in the competition this season.
Karim Benzema certainly repaid his manager's faith with a fantastic performance in midweek against Napoli.
The French forward has now scored in four consecutive Champions League matches this campaign but he needs to translate that form into the league.
James Rodríguez returned from injury against Osasuna and he started in midweek so it wouldn't be a surprise should Zidane give him a rest this weekend.